Discover how the HEK293-derived Pro10™ cell line accelerates AAV vector production. This whitepaper explores a scalable, animal component-free platform that reduces process development time and costs, meeting growing clinical and commercial demands for gene therapies.
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February 06, 2023
White paper: A proprietary mammalian suspension technology for scalable rAAV production: The Pro10™ cell line
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Webinar: Addressing Manufacturing and Characterization Challenges and Opportunities with Novel AAV Capsids
As capsid development becomes a higher priority for AAV gene therapy innovators, a fundamental shift is underway: Development teams are relying less on common capsid library options and more on rationally designed and directed methods to generate...
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June 02, 2026
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Repeatability and Intermediate Precision of a Genome Integrity Assay for rAAV by Long-Read Sequencing
Truncated recombinant AAV genomes can compromise transgene expression and the therapeutic efficacy1 of gene therapy vectors, making genome integrity a critical quality attribute, highlighting the need for robust analytical methods. Long‑read...
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June 01, 2026
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ddPCR-Based Quantification and Fragment Analysis of Residual E1A in rAAV Products: Method Validation and Correlation with Total Host Cell DNA
Abstract Gene therapy using adeno-associated virus (AAV) vectors has emerged as a promising strategy, offering new hope for patients with genetic disorders. However, during rAAV manufacturing, residual host-cell DNA (hcDNA) and plasmid DNA from the...
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June 01, 2026