Resources

Scientific Poster: Development of an Analytical Method For AAV Capsid Protein For Use in Stability Studies

This study highlights the importance of monitoring viral capsid protein charge distribution in AAV gene therapy vectors to ensure product quality. Using imaged capillary isoelectric focusing (icIEF), we developed a method to detect charge heterogeneity due to post-translational modifications, such as deamidation, which can reduce vector potency.

Please review the following rules: