---
title: "Scientific Poster: Development of an Analytical Method For AAV Capsid Protein For Use in Stability Studies"
description: This study highlights the importance of monitoring viral capsid protein charge distribution in AAV gene therapy vectors to ensure product quality. Using imaged capillary isoelectric focusing (icIEF), we developed a method to detect charge heterogeneity due to post-translational modifications, such as deamidation, which can reduce vector potency.
---

[Resources | Viralgen ](https://viralgen.com/resources)

# [Scientific Poster: Development of an Analytical Method For AAV Capsid Protein For Use in Stability Studies](https://viralgen.com/resources/development-of-an-analytical-method-for-aav-capsid-protein-for-use-in-stability-studies)

 Written by [Viralgen](https://viralgen.com/resources/author/viralgen) | May 3, 2024 1:00:00 PM

This study highlights the importance of monitoring viral capsid protein charge distribution in AAV gene therapy vectors to ensure product quality. Using imaged capillary isoelectric focusing (icIEF), we developed a method to detect charge heterogeneity due to post-translational modifications, such as deamidation, which can reduce vector potency.

[View full post](https://viralgen.com/resources/development-of-an-analytical-method-for-aav-capsid-protein-for-use-in-stability-studies)

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